HEALTHY READS

References

Adrenal Support Formula

“Management of adrenal insufficiency in different clinical settings.” Expert Opin Pharmacother. 2005 Nov;6(14):2407-17

“DHEA therapy for women: effect on sexual function and wellbeing.” Hum Reprod Update. 2007 Jan 5

“Vitamin C Supplementation attenuates the increases in circulating cortisol, adrenaline and anti-inflammatory polypeptides following ultramarathon running.” Int J Sports Med. 2001 Oct;22(7):537-43

“Nutritional and botanical interventions to assist with the adaptation to stress.” Altern Med Rev. 1999 Aug;4(4):249-65

Coleman, CI. et al. “The effects of Panax ginseng on quality of life.” J Clin Pharm Ther. 2003 Feb;28(1)5-15

Gaffney, BT. et al. “Panax ginseng and Eleutherococcus senticosus may exaggerate an already existing biphasic response to stress via inhibition of enzymes which limit the binding of stress hormones to their receptors.” Med Hypoheses. 2001 May;56(5):567-72

Lieberman HR. “The effects of ginseng, ephedrine, and caffeine on cognitive performance, mood, and energy.” Nutr Rev. 2001 Apr;59(4):91-102

Wang, LC. et al. “Effect of ginseng saponins on exercise performance in non-trained rats.” Planta Med. 1998 Mar;64(2):130-3

Grandhi, A. et al. “A comparative pharmacological investigation of Ashwagandha and Ginseng.” J Ethnopharmacol. 1994 Dec;44(3):131-5

Mrtinez, B. et al. “The physioogicl effects of Aralia, Panax and Eleutherococcus on exercised rats.” Jpn J Pharmacol. 1984 Jun;35(2):79-85

Panossian, A. et al. “Stimulating effect of adaptogens: an overview with particular reference to their efficacy following single dose administration.” Phytother Res. 2005 Oct;19(10):819-38

Goulet, ED. et al. “Assessment of the effects of eleutherococcus senticosus on endurance performance.” Int J Sport Nutr Exerc Metab. 2005 Feb;15(1):75-83

Bu, Y. et al. “Siberian ginseng reduces infarct volume in transient focal cerebral ischaemia in Sprague-Dawley rats.” Phytother Res. 2005 Feb;19(2):167-9

Kimura, Y. et al. “Effects of various Eleutherococcus senticosus cortex on swimming time, natural killer activity and corticosterone level in forced swimming stressed mice.” J Ethnopharmacol. 2004 Dec;95(2-3):447-53

Cicero, AF. et al. “Effects of Siberian ginseng (Eleutherococcus senticosus maxim.) on elderly quality of life: a randomized clinical trial.” Arch Gerontol Geriatr Suppl. 2004;(9):69-73

Hartz, AJ. et al. “Randomized controlled trial of Siberian ginseng for chronic fatigue.” Psychol Med. 2004 Jan;34(1):51-61

Arushanian, EB. et al. “[Effect of Eleutherococcus on short-term memory and visual perception in healthy humans.] [Article in Russian.]” Eksp Klin Farmakol. 2003 Sep-Oct;66(5):10-13

Abidov, M. et al. “Effect of extracts from Rhodiola rosea and Rhodiola crenulata (Crassulaceae) roots on ATP content in mitochondria of skeletal muscles.” Bull Exp Biol Med. 2003 Dec;136(6):585-7

De Bock, K. et al. “Acute Rhodiola rosea intake can improve endurance exercise performance.” Int J Sport Nutr Exerc Metab. 2004 Jun;14(3):298-307

Iremii, IN. et al. “[Hepaprotective properties of liquid extract of Rhodiola rosea.] [Article in Russian.]” Eksp Klin Farmakol. 2002 Nov-Dec;65(6):57-9

Petkov, VD. et al. “Effects of alcohol aqueous extract from Rhodiola rosea L. roots on learning and memory.” Acta Physiol Pharmacol Bulg. 1986;12(1):3-16

Pogorelyi, VE. et al. “[Rhodiola roase extract for prophylaxis of ischemic cerebral circulation disorder.] [Article in Russian.]” Eksp Klin Farmakol. 2002 Jul-Aug;65(4):19-22

Maslova, LV. et al. “[The cardioprotective and antiadrenergic activity of an extract of Rhodiola rosea in stress.] [Article in Russian.]” Eksp Klin Farmakol. 1994 Nov-Dec;57(6):61-3

Lishmanov, IuB. et al. “[The anti-arrhythmia effect of Rhodiola rosea and its possible mechanism.] [Article in Russian.]” Biull Eksp Biol Med. 1993 Aug;116(8):175-6

Salikhova, RA. et al. “[Effect of Rhodiola rosea on the yield of mutation alterations and DNA repair in bone marrow cells.] [Article in Russian.] Patol Fiziol Eksp Ter. 1997 Oct-Dec;(4):22-4

Dhuley, JN. et al. “Adaptogenic and cardioprotective action of ashwagandha in rats and frogs.” J Ethnopharmacol. 2000 Apr;70(1):57-63

Maity, TK. et al. “Effect of Ocimum sanctum (Holy Basil) roots extract on swimming performance in mice.” Phytother Res. 2000 Mar;14(2):120-1

Geeta et al. “Activity of Ocimum sanctum (the traditional Indian medicinal plant) against the enteric pathogens.” Indian J Med Sci. 2001 Aug;55(8):434-8, 472

Ganasoundari A. et al. “Protection against radiation-induced chromosome damage in mouse bone marrow by Ocimum sanctum.” Mutat Res. 1997 Feb 3;373(2)271-6

Dhuley, JN. et al. “Nootropic-like effect of ashwagandha (Withania somnifera L.) in mice.” Phytother Res. 2001 Sep;15(6):524-8

Mishra LC. et al. “Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review.” Altern Med Rev. 2000 Aug;5(4):334-46

Bucci, LR. “Selected herbals and human exercse performance.” Am J Clin Nutr. 2000 Aug;72(2 Suppl):624S-36S

Murase, T. et al. “Green tea extract improves endurance capacity and increases muscle lipid oxidation in mice.” Am J Physiol Regul Integr Comp Physiol. 2005 Mar;288(3):R708-15

Rao, SB. et al. “Centella asiatica treatment during postnatal period enhances learning and memory in mice.” Physiol Behav. 2005 Nov 15;86(4):449-57

Subathra, M. et al. “Emerging role of Centella asiatica in improving age-related neurological antioxidant status.” Exp Gerontol. 2005 Aug-Sep;40(8-9):707-15

Veerendra, KMH. et al. “Effect of Centella asiatica on cognition and oxidative stress in an intracerebroventricular streptozotocin model of Alzheimer’s disease in rats.” Clin Exp Pharmacol Physiol. 2003 May-Jun;30(5-6):336-42

Khanna, S. et al. “Alpha-lipoic acid supplementation: tissue glutathione homeostasis at rest and after exercise.” J Appl Physiol. 1999 Apr;86(4):1191-6

Barbiroli, B. et al. “Lipoic (thioctic) acid increases brain energy availability and skeletal muscle performance as shown by in vivo 31P-MRS in a patient with mitochondrial cytopathy.” J Neurol. 1995 Jul;242(7):472-7

Advanced Men’s Formula

“Hot Spice Kills 80% of Prostate Cancer Cells.” Prescriptions for Healthy Living. 2006 May;5(5):1-7

Lichius, JJ. et al. “Urtica dioica agglutinin (UDA)-treatment of experimental induced mouse prostatic hyperplasia.” FASEB Journal. 1997;11(3):A601

Odenthal, KP. et al. “Phytotherapy of benign prostatic hyperplasia (BPH) with Cucurbita, Hypoxis, Pygeum, Urtica and Sabal serrulata (Serenoa repens).” Phytotherapy Research. 1996;10(1):S141-3

Belaiche, P. et al. “Clinical studies on the palliative treatment of prostatic adenoma with extract of Urtica root.” Phytotherapy Research. 1991;5(6):267-9

Chaurasia, N. et al. “Sterols and seryl glycosides from Urtica dioica.” Journal of Natural Products. 1987;50(5):881-5

Wagner, H. et al. “Search for the antiprostatic principle of stinging nettle (Urtica dioica) roots.” Phytomedicine. 1994;1(3):213-24

Vahlensieck, W. et al. “[Drug therapy of benign prostatic hyperplasia.] [Article in German.]” Fortschr Med. 1996 Nov 10;114(31):407-11

Krzeski, T. et al. “Combined extracts of Urtica dioica and Pygeum africanum in the treatment of benign prostatic hyperplasia: double-blind comparison of two doses.” Clin Ther. 1993 Nov-Dec;15(6):1011-20

LaValle, J. “Men’s prostate health: a variety of key nutrients may play a role in prevention.” Drug Store News. 1997 Jul 14;19(11)

Shultz, TD. et al. “In-vitro inhibition of human and H238 cancer cell growth by high levels of pyridoxine and pyridoxal.” Fed Proc. 1987;46(4)

Mori, K. et al. “Effects of megadoses of pyridoxine on spermatogenesis and male reproductive organs in rats.” Arch Toxicol. 1992;66(3):198-203

Brown, DJ. “Saw palmetto: herbal prescription for treatment of BPH.” Drug Store News for Pharmacists. 1995 Apr;5:29-30

DeSilverio, F. et al. “Evidence that Serenoa repens extract displays an antiestrogenic activity in prostatic tissue of benign prostatic hypertrophy patients.” Eur Urol. 1992;21:309-14

Webach, Melvyn R. and Michael T. Murray. Botanical Influences on Illness. Third Line Press. Tarzana, CA:1994

B-Complex

“Joint FAO/WHO Expert Consultation on Human Vitamin and Mineral Requirements.” Bangkok, Thailand, 1998 Sep:164-193, 279-288

Hanninen, S. et al. “The Prevalience of Thiamin deficiency in Hospitalized Patients with Congestive Heart Failure.” J Am Coll Cardiol. 2006;47:354-361

McComsey, G. et al. “High Dose of Riboflavin and Thiamine May Help in Secondary Prevention of Hyperlactatemia.” AIDS Read. 2002;12(5):222-4

Zhang, S. “Folate, vitamin B6, multivitamin supplements, and colorectal cancer risk in women.” Am J Epidemiol. 2006 Jan 15;163(2) 108-115

Joosten, E. “Metabolic evidence that deficiencies of vitamin B-12 (cobalamin), folate, and vitamin B-6 occur commonly in elderly people.” Am J Clin Nutr. 1993,58:468-76

Tucker, K. “Breakfast cereal fortified with folic acid, vitamin B-6, and vitamin B-12 increases vitamin concentrations and reduces homocysteine concentrations: a randomized trial.” Am J Clin Nutr. 2004;79:805-11

“Thiamine deficiency and its prevention and control in major emergencies.” A formal publication of WHO. 1999

Johnson, L. “Study says B vitamins are good to bones.” Orange County Register. 2004 May 13.

“Albrecht, F. “How Folic Acid, B12 and B6 Promote Youthful Aging.” Health & Nutrition Breakthoughs. 1998 Feb:40-42

Rheinhart-Martin, J. “Energy Generators: a close-up on the B vitamins.” Energy Times. 2001 Nov-Dec:51-4

Alvarez, O. et al. “Thiamine influence on collagen during the granulation of skin wounds.” Journal of Surgical Research. 1982 Jan;32(1):24-31

Krapels, I. et al. “Maternal dietary B vitamin intake, other than folate, and the association with orofacial cleft in the offspring.” European Journal of Nutrition. 2004 Feb;43(1):7-14

Hernandez, B. et al. “Diet and premalignant lesions of the cervix: evidence of a protective role for folate, riboflavin, thiamin, and vitamin B12.” Cancer Causes and Control. 2003 Nov;14(9):859-870

Beta-Sitosterol

Z Naturforsch. 2000 May-June;55(5-6):485-8 [“The in vitro anti-fungal and anti-bacterial activities of beta-sitosterol from Senecio lyratus.”]

Hua Xi Yi Ke Da Xue Xue Bao. 1992 Mar; 23(1):98-101

Bio Pharm Bull. 2006 July; 29(7):1418-22 [“Identification of five phytosterols from Aloe vera gel as anti-diabetic compounds.”]

Altern Med Rev. 2001 Apr; 6(2):203-6 [“Monograph. Plant sterols and sterolins.”]

J Nutr. 2000 Jan;130(1):15-20 [“The traditional plant treatment, Sambucus nigra (elder) exhibits insulin-like and insulin-releasing actions in vitro.”]

Horm Metab Res. 1992 Apr; 2(4):172-5 [“Plasma non-cholesterol sterols in patients with non-insulin dependent diabetes mellitus.”]

Pharmazie. 1990 Apr;45(4):271-3 [“Effect of beta-sitosterol-3-beta-D-glucoside on insulin secretion in vivo in diabetic rats and in vitro in isolated rat islets of Langerhans.”]

J Lipid Res. 1985 Jan;26(1):62-9 [“Evaluation of the contribution of dietary cholesterol to hypercholesterolemia in diabetic rats and of sitosterol as a recovery standard for cholesterol absorption.”]

Natural Medicines Comprehensive Database. Beta-sitosterol. www.naturaldatabase.com

Null, Gary. The Complete Encyclopedia of Natural Healing. Bottom Line Books, Greenwich, CT: 2002.

Prevention’s Healing with Vitamins. Rodale Press, United States: 1996

Nutrition and Cancer. 2000;36(2):238-241 [“Peanuts as a source of beta-sitosterol, a sterol with anticancer properties.”]

American Society for Nutritional Sciences J. Nutr. 2003 June;133:1937-1942 [“Risk of human ovarian cancer is related to dietary intake of selected nutrients, phytochemicals and food groups.”]

American Society for Nutritional Sciences J. Nutr. 2004 May;134:1145-1151 [“Beta-sitosterol, beta-sitosterol glucoside, and a mixture of beta-sitosterol and beta-sitosterol glucoside modulate the growth of estrogen-responsive breast cancer cells in vitro and in ovariectomized athymic mice.”]

Med Hypotheses. 1981 May;7(5):601-13 [“The consumption of seaweed as a protective factor in the etiology of breast cancer.”]

Anticancer Res. 2000 Mar-Apr;20(2A):821-4 [“Dietary phytosterol inhibits the growth and metastasis of MDA-MB-231 human breast cancer cells grown in SCID mice.”]

Eur J Obstet Gynecol Reprod Biol. 2005 Dec 1;123(2):139-49 [“Nutrition and primary prevention of breast cancer: foods, nutrients and breast cancer risk.”]

Neoplasma. 2004;51(6):407-14 [“Taraxasterol and beta-sitosterol: new naturally compounds with chemoprotective/chemopreventive effects.”]

Chattopadhyay, D. et al. “Dose-dependent therapeutic antiinfectives from ethnomedicines of bay islands.” Chemotherapy. 2006;52(3):151-7

Kiprono, PC. Et al. “The in vitro anti-fungal and anti-bacterial activities of beta-sitosterol from Senecio lyratus (Asteraceae).” Z Naturforsch. 2000 May-Jun;55(5-6):485-8

Donald, PR. Et al. “A randomized placebo-controlled trial of the efficacy of beta-sitosterol and its glucoside as adjuvants in the treatment of pulmonary tuberculosis.” Int J Tuberc Lung Dis. 1997 Dec;1(6):518-22

Wilt, T. et al. “Beta-sitosterols for benign prostatic hyperplasia: a systematic review.” BJU Int. 1999 Jun;83(9):976-83

Ovesna, Z, et al. “Taraxasterol and beta-sitosterol: new naturally compounds with chemoprotective/chemopreventative effects.” Neoplasma. 2004;51(6):407-14

Big Blue I & II

Stanislavov, R. et al. “Treatment of erectile dysfunction with pycnogenol and L-arginine.” Journal of Sex & Marital Therapy. 2003 May;29(3):207-13

Cicero, AFG. et al. “Lepidium meyenii Walp. improves behavior in male rats independently from its action on spontaneous locomotor activity.” Journal of Ethnopharmacology. 2001 May;75(2-3):225-9

Panser, LA. et al. “Sexual function of men ages 40-79 years: the Olmsted County Study of Urinary Symptoms and Health Status Among Men.” J Am Geriatr Soc. 1995 Oct;43(10):1107-11

“The Dark Side of Viagra: Erectile Dysfunction Drugs and Vision Problems.” Worst Pills, Best Pills. 2005 Aug;11(8):57-9

Wright, J. “Back in the saddle without Viagra: New research gives hope to men with sexual dysfunction.” Nutrition & Healing. 2006 Jun;13(5)

“Estrogen dominance – why your manhood is vanishing! Fight the feminizing effects of estrogen with progesterone.” The McAlvany Health Alert. 2004 Aug;4(8):1-8

Preuss, H. et al. “A Critical Review of Cernitin for Symptomatic Relief of Lower Urinary Tract Symptoms (LUTS) in Men.”

Viktorov, I. et al. “Pharmacological, pharmacokinetic, toxicological and clinical studies on protodioscin.” Higher Medical Institute, Bulgaria. 1994

Wang, B. et al. “[406 cases of angina pectoris in coronary heart disease treated with saponin of Tribulus terrestris.] [Article in Chinese.]” Chinese Journal of Modern Developments in Traditional Medicine. 1990 Feb;10(2):85-7

Dimitrov, M. et al. “[Use of tribestan on rams with sexual disorders.] [Article in Bulgarian.]’ Veterinarno-Meditsinski Nauki. 1987;24(5):102-110

Cayenne with Ginger

Kawada, T. et al. “Effects of Capsaicin on Lipid Metabolism in Rats Fed a High Fat Diet.” Journal of Nutrition. 1986;116:1272-8

Visudhiphan, S. et al. “The relationship between high fibrinolytic activity and daily capsicum ingestion in Thais.” American Journal of Clinical Nutrition. 1982 Jun;35:1452-8

Lien, H. et al. Effects of ginger on motion sickness and gastric slow-wave dysrhythmias induced by circular vection.” Am J Physiol Gastrointest Liver Physiol. 2002 Oct;284:G481-9

Vutyavanich, T. et al. “Ginger for Nausea and Vomiting in Pregnancy: Randomized, Double-Masked, Placebo-Controlled Trial.” Obstetrics & Gynecology. 2001 Apr;97(4):577-82

“Hot Spice Kills 80% of Prostate Cancer Cells.” Prescriptions for Healthy Living. 2006 May;5(5):1-7

Fox, M. “Ginger, Pepper treat difficult cancers.” Reuters Health and Science. 2006 Apr 4.

“Pepper extract could stop prostate cancer growth.” Decision News Media SAS / NutraIngredients-USA. 2006 Mar 15.

Lee, C. et al. “Short-term control of capsaicin on blood and oxidative stress of rats in vivo.” Phytotherapy Research. 2003 May;17(5):454-8

Al-Amin, Z. et al. “Anti-diabetic and hypolipidaemic properties of ginger (Zingiber officinale) in streptozotocin-induced diabetic rats.” British Journal of Nutrition. 2006;96:660-6

Brett, Jennifer. “Cayenne pepper: Herbal remedies.”

O’Connor, A. “The claim: Eating ginger can cure motion sickness.” The New York Times: Health. 2001, Aug 21.

Cell Talk

Liu, JM. et al. “[Chemical constituents of Cordyceps mililaris.] Zhongguo Zhong Yao Za Zhi. 1989 Oct;14(10)608-9, 639

Bucci, LR. “Selected herbals and human exercise performance.” Am J Clin Nutr. 2000 Aug;72(2 Suppl):624S-36S

Granato, H. “Enhancing Immune Function.” Natural Products Marketplace. 2007 Apr:16-28

“Apply enzymes and glycobiology to product development.” Emerging Food R&D Report. 1998 Nov 1;9(8)

Choi, CQ. “Glycomics researchers search for the elusive sweet spot.” The Scientis. 2005, Mar 28;19(6)30-1

Elkins, R. Miracle Sugars: The New Missing Nutrients. Woodland, Utah:2002

Green-Bishop, J. “The healing of a healer.” Dallas Weekly Reprint. 2004 Feb.

Tran, C. “Spotlight on stem cells.” Orange County Register. 2007, Mar 5.

Myers, S. “Basic Instinct: Immunity.” HSR Health Supplement Review. 2006, Aug.;14-25

Chicken Sternal Collagen

Duarte, Alex. The Collagen Type II Cure for Arthritis & Heart Disease. 1997.

Gorman, Christine, and Alice Park. “The Fires Within.” Time. 2004 Feb 23; 39-45.

Stuhlmeier, KM. “Aspects of the biology of hyaluronan, a largely neglected but extremely versatile molecule.” Wien Med Wochenschr. 2006 Nov;156(21-22):563-8

Li, G. et al. “Serum concentrations of hyaluronic acid, procollagen type III NH2-terminal peptide, and laminin in patients with chronic congestive heart failure.” Chin Med Sci J. 2006 Sep; 21(3):175-8

Dobaczewski, M. et al. “Extracellular matrix remodeling in canine and mose mydocardial infarcts. Cell Tissue Res. 2006 Jun;324(3):475-88

Tsukihara, H. et al. “Prevention of postoperative pericardial adhesions with a novel regenerative collagen sheet.” Ann Thorac Surg. 2006 Feb;81(2):650-7

Farb, A. et al. “Extracellualr matrix changes in stented human coronary arteries.” Circulation. 2004 Aug;110(8):940-7

Yasui, H. et al. “Altered distribution of collagen type I and hyaluronic acid in the cardiac outflow tract of mouse embryos destined to develop transposition of the great arteries.” Heart Vessels. 1997;12(4):171-8

Richy, F. et al. “Structural and Symptomatic efficacy of glucosamine and chondroitin in knee osteoarthritis.” Arch Intern Med. 2003;165:1514-22

Trentham, DE. Et al. “Effects of oral administration of type II collagen on rheumatoid arthritis.” Science. 1993 Sep 24

Buckman, K. et al. “Clinical Trials: Effects of collagen type II for subjective pain relief.” 1999 Mar

Bagchi, D. “Undenatured type II collagen for arthritis.” Natural Pharmacy. 2003 Mar/Apr:20

Choline Bitartrate

Zeisel, S. “Choline: Needed for Normal Development of Memory.” Journal of the American College of Nutrition 2000;19(5):528-531.

Zeisel, S. “Nutritional importance of choline for brain developent.” J Am Coll Nutr. 2004;23(6):621S-626S

Olthof MR. “Low dose betaine supplementation leads to immediate and long-term lowering of plasma homocysteine in healthy men and women.” J Nutr. 2003 Dec;133(12):4135-8

“Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects.” Am J Clin Nutr. 2002 Nov;76(5):961-7

Eussen SJ, et al. “The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people.” Br J Nutr. 2007 May 31;:1-9

Caamano J., et al. “Effects of CDP-choline on cognition and cerebral hemodynamics in patients with Alzheimer’s disease.” Exp Clin Pharmacol 1994 Apr;16)3):211-218

Da Costa, Kerry-Ann et al. “Choline deficiency in mice and humans is associated with increased plasma homocysteine concentration after a methionine load.” Am J Clin Nutr 2005;81:440-4

Da Costa, Kerry-Ann et al. “Choline deficiency increase lymphocye apoptosis and DNA damage in humans.” Am J Clin Nutr. 2006;84:88-94

Buchman, A. “Choline deficiency causes reversible hepatic abnormalities in patients receiving parental nutrition: Proof of a human choline requirement: A placebo-controlled trial.” Journal of Parental and Enteral Nutrition. 2001 Sep/Oct.

Artom, C. “Mechanism of action of hcoline.” Am J Clin Nutr. 1960 May/Jun;8:303-5

Stekol, J. “Biosynthesis of choline and betaine.” Am J Clin Nutr. 1958 May/Jun;200-15

Craig, S. “Betaine in human nutrition.” Am J Clin Nutr. 2004;80:539-49

“Choline recommendations may be too low, study.” NutraIngredients-USA. 2007 Jun.

Citrigenics® I

Heymsfield, S. et al. “Garcinia cambogia (Hydroxycitric Acid) as a potential antiobesity agent.” JAMA. 1998 Nov 11; 280(18):1596-1600

Hayamizu, K. et al. “Effects of garcinia cambogia (Hydroxycitric Acid) on visceral fat accumulation: a double blind, randomized, placebo-controlled trial.” Current Therapautic Research. 2003 Sep-Oct;64(8):551-567

Mahendran, P. et al. “The antiulcer activity of Garcinia cambogia extract against indomethacin-induced gastric ulcer in rats.” Phytotherapy Research. 2002 Jan 23;16(1):80-3

Koshy, A. et al. “Flavonoids from Garcinia cambogia lower lipid evels in hypercholesterolemic rats.” Food Chemistry. 2001 Feb;72(3):289-294

Coconut Oil

Fife, Bruce. The Miracle of Coconut Oil. Piccadilly Books, Colorado:2003

Enig, Mary G., Ph.D. “Health and Nutritional Benefits from Coconut Oil: An Important Functional Food for the 21st Century.” Presented April 25 1996, AVOC Lauric Oils Symposium, Ho Chi Min City, Vietnam.

Natural Medicines Comprehensive Database. Coconut Oil. www.naturaldatabase.com

Dayrit, Conrado S. “Coconut Oil in Health and Disease: Its and monolaurin’s potential as cure for HIV/AIDS.” Read at the XXXVII Cocotech Meeting, Chennai, India, July 25, 2000.

Prior IA, Davidson F, et al. “Cholesterol, coconuts, and diet on Polynesian atolls: A Natural Experiemnt: the Pukapuka and Tokelau island studies.” American Journal of Clinical Nutrition. 1981 Aug;34(8)1552-61

Sircar S, and Kansra U. “Choice of cooking oils – myths and realities.” Journal Indian Medical Association. 1998 Oct;96(10):304-7

GL Blackburn, et al “A reevaluation of coconut oil’s effect on serum cholesterol and atherogenesis.” Journal of the Philippine Medical Association 65:144-152;1989

LA Cohen, et al. “Dietary fat a mammary cancer. I. Promoting effects of different dietary fats on N-nitrosomethylurea-induced rat mammary tumorigenesis.” Journal of the National Cancer Institute 77:33;1986.

LA Cohen, et al. “Dietary fat a mammary cancer. II. Modulation of serum and tumor lipid composition and tumor prostaglandins by different dietary fats: Association with tumor incidence patterns.” Journal of the National Cancer Institute 77:43;1986.

Holzapfel, Cynthia and Laura Holzapfel. Coconut Oil for Health and Beauty. Book Publishing, USA:2003

“Are Trans fat substitutes really heathier?” CNN.com. 2007 Apr

Colon Essentials

Sachs, Jessica S. “Are antibiotics killing us?” Discover. 2005 Nov:38-40

Rowen, RJ. “The startling truth about coenzyme q10.” Second Opinion. 2001 Mar.

Shahani, K. Cultivate Health from Within. Vital Health, USA:2005

“Restoring the normal balance of gastrointestinal microorganisms.” Health Talk. 1990 Jun;9(1)

Steiner, E. “Take a probiotic stand against eat infections.” Essential Vitality. 2002 Fall/Winter:8-9

Gittleman, AL. “Probiotics-21st century heroes.” Total Health. 27(3);30-1

“Proactive digestive protection with probiotics.” Energy Times. 2001 May.

“Beyond Probiotics – dynamic cellular nutrients offers solid GI balance and a healthy colon.” Journal of Science & Health. 3(4):1-8

Haines, B. “Probiotics: Positive acting bacteria delivered through dairy foods.” Nutraceutical World. 2000 Apr;3(4): 70-85

“Probiotics build eczema resistance.” NutraIngredients-USA. 2003 May 5.

“Probiotic therapy helps recovery from surgery.” NutraIngredients-USA. 2004 Jan 6.

CoQ10

Shults, CW. et al. “Effects of coenzyme Q10 in early Parkinson’s disease: evidence of slowing of the functional decline.” Arch Neurol. 2002 Oct;59(10):1541-50

Natural Medicines Comprehensive Database. Coenzyme Q10. www.naturaldatabase.com

Horvath, TL. et al. “Coenzyme Q induces nigral mitochondrial uncoupling and prevents dopamine cell loss in a primate model of Parkinson’s disease.” Endocrinology 2003;144(7):2757-2760

Faloon, W. “Has your CoQ10 Become Obsolete?” Life Extension. 2007 Jan;23-31

“Effect of the Supplemental Use of Antioxidants Vitamin C, Vitamin E, and the Coenzyme Q 10 for the Prevention and Treatment of Cancer.” ARHQ Publications Clearinghouse Evidence Report/Technology Assessment No. 3. 2003 Oct.

Sinatra, S. Coenzyme Q10 and the Heart. McGraw-Hill, 1999

Johannes, L. “Giving an ailing heart a boost with a supplement.” Wall Street Journal: Aches & Claims. 2007 Mar 27.

“CoEnzyme Q10: Patient Version.” National Cancer Institute. Accessed 2007 Nov 26.

DHA

Pfrommer, C. et al. “Docosahexaenoic acid induces ciap1 mRNA and protects human endothelial cells from stress-induced apoptosis.” Am J Physiol Heart Circ Physiol. 2006;290:H2178-H2186

Stordy, BJ. “Dark adaptation, motor skills, docosahexaenoic acid, and dyslexia.” Am J Clin Nutr. 2000;71(suppl):323S-326S

Marangell, L. et al. “A double-blind, placebo-controlled study of the omega-3 fatty acid docosahexaenoic acid in the treatment of major depression.” Am J Psychiatry. 2003;160:996-8

Shoji, H. et al. “Effect of docosahexaenoic acid and eicosapentaenoic acid supplementation on oxidative stress levels during pregnancy.” Free Radical Research. 2006 Apr;40(4):379-84

Woodman, R. et al. “Effects of purified eicosapentaenoic and docosahexaenoic acids on glycemic control, blood pressure, and serum lipids in type 2 diabetic patients with treated hypertension.” Am J Clin Nutr. 2002;76:1007-15

Doaud, Clarisse. “Scientists connect DHA to warding off symptoms of Parkinson’s.” NutraIngredients-USA. 2007 Nov 27.

“Omega-3 fatty acid may help prevent Alzheimer’s brain lesions: study suggest DHA-rich diet can curb onset of the disease.” UC Irvine. 2007 Apr 17.

Digestive Balance

Bitomsky, M. “Digestive Enzymes: The Missing Link.” Life Extension. 1999 Apr:22-6

“Coping with digestive distress.” Health Products Business. 1999 Jun:20-4

Lawrence, R.M. “Danger of antacids exposed and a safer alternative revealed in new research breakthrough.”

Epithelial Tissue Support

“Pomegranate juice reduces risk of brain injuries in babies.” Agence France-Presse. 2005 Jun 30.

Kichenin, K. “Cardiovascular and pulmonary response to oral administration of ATP in rabbits.” J Appl Physiol. 2000;88:162-8

Jordan, A.N. “Effects of oral ATP supplementation on anaerobic power and muscular strength.” Med Sci Sports Exerc. 2004 Jun;36(6):983-90

Essentials for Women

“Low vitamin D status in mother-newborn pairs in Greece.” Calcif Tissue Int. 2006 Jun;78(6):337-42

“Does vitamin K prophylaxis prevent bleeding in neonates exposed to enzyme-inducing antiepileptic drugs in utero?” Can Fam Physician. 2006 Jun;52:721-2

“Vitamin A supplementation increases ratios of proinflammatory to anti-inflammatory cytokine responses in pregnancy and lactation.” Clin Ep Immunol. 2006 Jun;144(3):392-400

“Changes in calcium, 25(OH) vitamin D3 and other biochemical factors during pregnancy.” J Endocrinol Invest. 2006 Apr;29(4): 303-7

“Association of low intake of milk and vitamin D during pregnancy with decreased birth weight.” CMAJ. 2006 Apr;174(9):1273-7

“Improvements in the status of folate and cobalamin in pregnant Newfoundland women are consistent with observed reductions in the incidence of neural tube defects.” Can J Public Health. 2006 Mar-Apr;97(2):132-5

“Predictors of early postpartum vitamin use among women of Mexican origin: implication for healthcare provider recommendations.” Ethn Dis. 2006 Winter;16(1):194-200

“Prenatal vitamin C status is associated with placental apoptosis in normal-term human pregnancies.” Placenta. 2006 Mar 22

“[Evaluation of selected vitamins and minerals intake in pregnant women] [Article in Polish].” Rocz Panstw Zakl Hig. 2005;56(3):245-51

“Polyunsaturated fatty acid supplementation during pregnancy alters neonatal behavior in sheep.” J Nutr. 2006 Feb;136(2):397-403

“Use of over-the counter medications and herbal remedies in pregnancy.” Am J Perinatol. 2005 Aug;22(6):321-4

“Maternal use of nutritional supplements during the first month of pregnancy and decreased risk of Down’s syndrome: case-control study.” Nutrition. 2005 Jun;21(6):698-704

“Role of trace elements zinc, copper and magnesium during pregnancy and its outcome.” Indian J Pediatr.2004 Nov;71(11):1003-5

“Antioxidant intake in pregnancy in relation to wheeze and eczema in the first two years of life.” Am J Respir Crit Care Med. 2005 Jan 15;171(2):121-8

“Multivitamin use and the risk of preterm birth.” Am J Epidemiol. 2004 Nov 1;160(9):886-92

“Maternal dietary B vitamin intake, other than folate, and the association with orofacial cleft in the offspring.” Eur J Nutr. 2004 Feb;43(1):7-14

“Fish oil supplementation of rats during pregnancy reduces adult disease risk in their offspring.” J Nutr. 2003 Oct;133(10):3170-4

“Prenatal vitamin supplementation and risk of childhood brain tumors.” Int J Cancer Suppl. 1998;11:17-22

“Evaluation of prenatal vitamin-mineral supplements.” Clin Pharm. 1987 Oct;6(10):770-7

EFAs

Stoll, BA. “Essential Fatty Acids, insulin resistance, and breast cancer risk.” Nutr Cancer. 1998;31(1):72-7

Gebauer, S. et al. “n-3 Fatty acid dietary recommendations and food sources to achieve essentiality and cardiovascular benefits.” Am J Clin Nutr. 2006;83(suppl):1526S-35S

Maixent, JM et al. “Dietary fish oil promotes positive intropy of ouabain in the rat heart.” Am J Physiol. 1999;277(Heart Circ. Physiol. 46): H2290-7

Goel, D. et al. “Effects of n-3 polyunsaturated fatty acids on cardiac sarcolemmal Na+/H+ exchange.” Am J Physiol Heart Circ Physiol. 2002;283:H1688-94

Lemaitre, R. et al. “n-3 Polyunsaturated fatty caids, fatal ischemic heart disease, and nonfatal myocardial infarction in older adults: the Cardiovascular Health Study.” Am J Clin Nutr. 2003;77:319-25

Kris-Etherton, P. et al. “Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease.” Circulation. 2002;106:2747-57

“Effects of omega-3 fatty acids on cardiovascular disease.” Agency for Healthcare Research and Quality. 2004;94:1-7

Djousse, L. et al. “Dietary linolenic acid is inversely associated with calcified atherosclerotic plaque in the coronary arteries.” Circulation. 2005;111:2921-26

Erkkila, A. et al. “n-3 Fatty acids and 5-y risks of death and cardiovascular disease events in patients with coronary artery disease.” Am J Clin Nutr. 2003;78:65-71

MacLean, CH, et al. “Effects of omega-3 fatty acids on cognitive function with aging, dementia, and neurological diseases.” Agency for Healthcare Research and Quality. 2005;114:1-3

Schachter, HM et al. “Effects of omega-3 fatty acids on mental health.” Agency for Healthcare Research and Quality. 2005;116:1-11

Beltz, B. S. et al. “Omega-3 fatty acids upregulate adult neurogenesis.” Neurosci Lett. 2001 Mar 26;415(2):154-8

Whalley, L. et al. “Cognitive aging, childhood intelligence, and the use of food supplements: possible involvement of n-3 fatty acids.” Am J Clin Nutr. 2004;80:1650-7

Mickleborough, T. et al. “Protective effect of fish oil supplementation on exercise-induced bronchoconstriction in asthma.” Chest. 2006;129:39-49

Mori, T. et al. “Dietary fish as a major component of a weight-loss diet: effect on serum lipids, glucose, and insulin metabolism in overweight hypertensive subjects.” Am J Clin Nutr. 1999;70:817-25

Parker, G. “Omega-3 fatty acids and mood disorders.” Am J Psychiatry. 2006;163:969-978

Pfrommer, C. et al. “Docosahexaenoic acid induces ciap1 mRNA and protects human endothelial cells from stress-induced apoptosis.” Am J Physiol Heart Circ Physiol. 2006;290:H2178-H2186

Stordy, BJ. “Dark adaptation, motor skills, docosahexaenoic acid, and dyslexia.” Am J Clin Nutr. 2000;71(suppl):323S-326S

Marangell, L. et al. “A double-blind, placebo-controlled study of the omega-3 fatty acid docosahexaenoic acid in the treatment of major depression.” Am J Psychiatry. 2003;160:996-8

Shoji, H. et al. “Effect of docosahexaenoic acid and eicosapentaenoic acid supplementation on oxidative stress levels during pregnancy.” Free Radical Research. 2006 Apr;40(4):379-84

Kelavkar, U. et al. “Prostate tumor growth and recurrence can be modulated by the [omega]-6:[omega]-3 ratio in diet: athymic mouse xenograft model stimulating radical prostatectomy.” Neoplasia. 2006 Feb;8(2):112-24

Lewin, GA et al. “Effects of omega-3 fatty acids on child and maternal health.” Agency for Healthcare Research and Quality. 118:1-11

Bonis, PA et al. “Effects of omega-3 fatty acids on organ transplantation.” Agency for Healthcare Research and Quality. 115:1-10

Wyrwoll, C. et al. “Prevention of programmed hyperleptinemia and hypertension by postnatal dietary omega-3 fatty acids.” Endocrinology. 2006;147(1):599-606

MacLean CH et al. “Effects of omega-3 fatty acids on cancer.” Agency for Healthcare Research and Quality. 2005;113:1-4

“Omega-3 could reduce neck and back pain.” NutraIngredients-USA 2006 May 2.

“Fish oils ease aggression.” NutraIngredients-USA 2004 Jan 26.

Decker, K. “The ABCs of Omega-3s.” Food Product Design. 2005 Feb;:81-91

Josephs, A. “An ‘executive order’ to include fish oil in your diet.” Vitacost For Your Health Newsletter. 2005 Apr 7.

Vitamin C

Joshi, K. et al. “Supplementation with flax oil and vitamin C improves the outcome of Attention Deficit Hyperactivity Disorder (ADHD).” Prostaglandins, Leukotreines, and Essential Fatty Acids. 2006 Jan;74(1):17-21

Bruno, R. et al. “Faster plasma vitamin E disappearance in smokers is normalized by vitamin C supplementation.” Free Radical Biology and Medicine. 2006 Feb;40(4):689-97

Sridulyakul, P. et al. “Vitamin C supplementation could reverse diabetes-induced endothelial cell dysfunction in mesenteric microcirculation in STZ-rats.” Clinical Hemoreology and Microcirculation. 2006;34(1-2):315-21

Raschke, T. et al. “Topical activity of ascorbic acid: from in vitro optimization to in vivo efficacy.” Skin Pharmacology and Physiology. 2004;17:200-6

Humbert, P. eet al. “Topical ascorbic acid on photodamaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo.” Experimental Dermatology. 2003 Jun;12(3):237-44

Hanratty, C. et al. “The effect on endothelial function on vitamin C during methionine induced hyperhomocysteinaemia.” BMC Cardiovascular Disorders. 2001;1

Kaufman, P. et al. “Coronary heart disease in smokers: Vitamin C restores coronary microcirculatory function.” Circulation. 2000;102:1233-1238

Timimi, TK. et al. “Vitamin C improves endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus." J Am Coll Cardiol. 1998;31:552-7

Mullan, B. et al. “Protective effects of ascorbic acid on arterial hemodynamics during acute hyperglycemia.” Am J Physiol Heart Circ Physiol. 2004;287:H1262-8

Monahan, K. et al. “Ascorbic acid increased cardiovagal baroreflex sensitivity in healthy older men.” Am J Physiol Heart Circ Physiol. 2004;286:H2113-7

Mak, S. et al. “Vitamin C prevents hyperoxia-mediated vasoconstriction and impairment of endothelium-dependent vasodilation.” Am J Physiol Heart Circ Physiol. 2002;282:H2414-21

Bagi, Z. et al. “Vascular signaling by free radicals. Oxidativ stress-induced dysregulation of arteriolar wall shear stress and blood pressure in hyperhomocysteinemia is prevented by chronic vitamin C treatment.” Am J Physiol Heart Circ Physiol. 2003; 285:H2277-83

Mak, S. “Effect of vitamin C and L-NMMA on the inotropic response to dobutamine in patients with heart failure.” Am J Physiol Heart Circ Physiol. 2005;289:H2424-8

Barclay, L. “High-dose vitamin C: a new therapeutic approach.” Life Extension. 2006 Oct:31-7

Levy, T.E. “Vitamin C, pulmonary embolism, and Cali, Colombia.” Vital Medical Responses. Vol.1 No.6

FiberBlend

Kelly, G. “Larch arabinogalactan: clinical relevance of a novel immune-enhancing polysaccharide.” Altern Med Rev. 1999;4(2):96-103

Grieshop, C. et al. “Oral administration of arabinogalactan affects immune status and fecal microbial populations in dogs.” J Nutr. 2002;132:478-82

Elkins, R. Miracle Sugars: The New Missing Nutrients. Woodland, Utah:2002
Ahmed, A. “Beta-Glucans: Natural modulators of immune responsiveness.” Natural Pharmacy. 2002 Nov/Dec;6(8):1,15,20

Potter, R. et al. “OatVantage oat beta-glucan: a unique soluble fiber for reduction of multiple cardiovascular risk factors.” OatVantage Scientific Review. 1

“Coronary heart disease health claim for OatVantage .” OatVantage Scientific Review. 1

“Immune System Breakthrough: You may never be sick again.” International Journal of Alternative Therapies. 1999 Summer;22: 1-2, 16-17

For Your Eyes Only
Natural Medicines Comprehensive Database. Beta-Carotene. www.naturaldatabase.com

Natural Medicines Comprehensive Database. Grape. www.naturaldatabase.com

Natural Medicines Comprehensive Database. Pomegranate. www.naturaldatabase.com

Freudenheim, JL. et al. “Premenopausal breast cancer risk and intake of vegetables, fruits, and related nutrients.” Jrnl Nat Cancer Inst. 1996 Mar 20;88(6) 340-8

Lewis, B. “Lutein and its relation to breast cancer.” Kemin Technical Literature. 2005

Fulghum Bruce, D. “Bilberry: Targeted Protection for the Eyes, Blood Vessels, and Heart.” Life Extension 2006 Nov:77-80

Cho, E. et al. “Prospective study of intake of fruits, vegetables, vitamins, and carotenoids and risk of age-related maculopathy.” Arch Opthamol. 2004;1222:883-92

Richer, S. et al. “Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration: the Veterans LAST study (Lutein Antioxidant Supplementation Trial).” Optometry. 2004 Apr;75(4):216-30

Kowluru, R.A. et al. “Effects of curcumin on retinal oxidative stress and inflammation in diabetes.” Nutrition & Metabolism. 2007 Apr;4:8

Wang, H. et al. “Oxygen Radical Absorbing Capacity (ORAC) of anthocyanins.” J. Agric. Food Chem. 1997;45:304-9

Brown, L. et al. “A prospective study of carotenoid intake and risk of cataract extraction in US men.” Am J Clin Nutr. 1999;70:517-24.

Pratt, S. “Dietary prevention of age-related macular degeneration.” Journal of the American Optometric Association. 1999 Jan;70(1):39-47

Wagner, E. “Lutein, zeaxanthin deficiencies linked to arterial disease.” Life Extension. 2006 Nov:15

Josephs, A.S. “Protect your precious eyesight.” Vitacost For Your Health Newsletter. 2005 Aug 4.

Lewis, B. “Lutein concentration during pregnancy and lactation.” Kemin Technical Literature. 2004

Rowen, Robert J. Powerful New Cures for Failing Vision. Second Opinion Publishing, Atlanta:2005

Muth, E. et al. “The effect of bilberry nutritional supplementation on night visual acuity and contrast sensitivity.” Altern Med Rev. 2000;5(2):164-73

FP-63

Swiss Flower Pollen: Nature’s Superfood for Energy, Allergies, the Prostate and Immunity. National Life Extension Research Institute:1999

Hurricane

“Medical curiosities by the numbers.” Orange County Register. 2004 Jan 14

Johnson, L.A. “Bacterial ‘superbugs’ pose deadly threat.” Orange County Register. 2004 Sep 30.

Hyaluronic Acid

Ventura, C. et al. “Hyaluronan mixed esters of butyric and retinoic Acid drive cardiac and endothelial fate in term placenta human mesenchymal stem cells and enhance cardiac repair in infracted rat hearts.” J Biol Chem. 2007 May 11;282(19) 14243-52
Stuhlmeier, KM. “Aspects of the biology of hyaluronan, a largely neglected but extremely versatile molecule.” Wien Med Wochenschr. 2006 Nov;156(21-22):563-8

Dobaczewski, M. et al. “Extracellular matrix remodeling in canine and mose mydocardial infarcts. Cell Tissue Res. 2006 Jun;324(3):475-88

Heublein, B. et al. “Polymerized degradable hyaluronan-a platform for stent coating with inherent inhibitory effects on neointimal formation in a porcine coronary model.” Int J Artif Organs. 2002 Dec;25(12):1166-73

Kolodgie, FD. “Differential accumulation of proteoglycans and hyaluronan in culprit lesions: insights into plaque erosion.” Arterioscler Thromb Vasc Biol. 2002 Oct 1;22(10):1642-8

Camenisch, TD. et al. “Disruption of hyaluronan synthase-2 abrogates normal cardiac morphogenesis and hyaluronan-mediated transformation of epithelium to mesenchyme.” J Clin Invest. 2000 Aug;106(3):349-60

Soderblom, T. et al. “High pleural fluid hyaluronan concentrations in rheumatoid arthritis.” Eur Respir J. 1999 Mar;13(3):519-22

Chajara A. et al. “Role of hyaluronic acid in the arterial response to angioplasty.” Pathol Biol (Paris). 1998 Sep;46(7):561-70

Atagi S. et al. “Utility of hyaluronic acid in pleural fluid for differential diagnosis of pleural effusions: likelihood ratios for malignant mesothelioma.” Jpn J Clin Oncol. 1997 Oct;27(5):293-7

Gerdin, B. et al. “Dynamic role of hyaluronan (HYA) in connective tissue activation and inflammation.” J Intern Med. 1997 Jul;242(1):49-55

Riessen, R. et al. “Distribution of hyaluronan during extracellular matrix remodeling in human restenotic arteries and balloon-injured rat carotid arteries.” Circulation. 1996 Mar;93(6):1141-7

Mitchell, JD. Et al. “Reduction in experimental pericardial adhesions using a hyaluronic acid bioabsorbable membrane.” Eur J Cardiothorac Surg. 1994;8(3):149-52

Swann, D. et al. “Role of hyaluronic acid in joint lubrication.” Ann. rheum. Dis. 1974;33:318

Armstrong, S. et al. “Relationship between lymph and tissue hyalutonan in skin and skeletal muscle.” Am J Physiol Heart Circ Physiol 2002 Aug;283:H2485-94

Kramer, K. et al. “Effective prevention of adhesions with hyalutonate.” Arch Sur.g 2002 Mar;137:278-82

Mochizuki, S. et al. “role of hyaluronic acid glycosaminoglycans in shear-induced endothelium-derived nitric oxide release.” Am J Physiol Heart Circ Physiol. 2003 May;285:H722-6

Ghatak, S. et al. “Hyaluronan oligosaccharides inhibit anchorage-independent growth of tumor cells by suppressing the phosphoinositide 3-kinase/akt cell survival pathway.” Journ Biol Chem. 2002 Oct;277(41):38013-20

Jalali, R. “Hyaluronic Acid.” Total Health. 26(4):60-1

Weindl, G. et al. “Hyaluronic acid in the treatment and prevention of skin diseases: molecular biological, pharmaceutical, and clinical aspects.” Skin Pharmacology and Physiology. 2004;17(5):207-13

Immortale for Men

Folia Microbiol (Praha). 1996;41(5):407-12 [“Antifungal properties of yam peel extract.”]

Bucci, LR. “Selected herbals and human exercise performance.” Am J Clin Nutr. 2000 Aug;72(2 Suppl):624S-36S

Delgado, N. “Estrogen dominance: a newly discovered male toxin?” Anti-Aging Medical News. 2003 Winter:7,14,22-23,28,39,41,45,49

Walker, M. “Adaptogens: Natures answer to stress.” 1994

Immortale for Women

Folia Microbiol (Praha). 1996;41(5):407-12 [“Antifungal properties of yam peel extract.”]

Bucci, LR. “Selected herbals and human exercise performance.” Am J Clin Nutr. 2000 Aug;72(2 Suppl):624S-36S

Walker, M. “Adaptogens: Natures answer to stress.” 1994

Rocky’s Iron

Dallman, P. “Iron deficiency and the immune response.” Am J Clin Nutr. 1987;46:329-34

Ahluwalia, N. et al. “Immune function in impaired in iron-deficient, homebound, older women.” Am J Clin Nutr. 2004;79:516-21

Zhou, S. et al. “Effect of iron supplementation during pregnancy on the intelligence quotient and behavior of children at 4 y of age: long-term follow-up of a randomized controlled trial.” Am J Clin Nutr. 2006;83:1112-7

Kuvibidila, S. et al. “Influence of iron-deficiency anemia on selected thymus functions in mice: thymulin biological activity, T-cell subsets, and thymocyte proliferation.” Am J Clin Nutr. 1990;51:228-32

Beard, J. et al. “Iron status and exercise.” Am J Clin Nutr. 2000;72(suppl):594S-7S

Strauss, R.G. “Iron deficiency, infections, and immune function: a reassessment.” Am J Clin Nutr. 1978 Apr;31:660-6

Carnielli, V. et al.“Iron supplementation enhances response to high doses of recombinant human erythropoietin in preterm infants.” Arch Dis Child Fetal Neonatal Ed. 1998;79:F44-8

Black, M..M. et al. “Iron and zinc supplementation promote motor development and exploratory behavior among Bangladeshi infants.” Am J Clin Nutr. 2004;80:903-10

Lee, S. et al. “Iron supplementation inhibits cough associated with ACE inhibitors.” Hypertension. 2001;38:166-70

Bruner, A.B. et al. “Randomised study of cognitive effects of iron supplementation in non-anaemic iron-deficient adolescent girls.” The Lancet. 1996 Oct 12;348(9033):992-6

Kidney and Bladder Support

Planta Med. 2005 Jan;71(1):67-71 [“Antimicrobial activity of sesquiterpenes from the essential oil of Juniperus thurifera.”]

Lights Out

Golbin, A. “Antioxidants may help you catch more productive Zzzs.” Total Health. 27(3):28-9

Wright, J. “Sleep your way to cancer prevention.” Nutrition & Healing. 2006 Dec;13(10)1-2

“Circadian Rhythms: How your body’s internal clock affects your health.” Mayo Clinic Women’s HealthSource. 2002 Oct:4-5.

Gyllenhaal, C. et al. “Efficacy and safety of herbal stimulants and sedatives in sleep disorders.” Sleep Med Rev. 2000 Jun;4(3):229-51

Wheatley, D. “Medicinal plants for insomnia: a review of their pharmacology, efficacy, and tolerability.” J Psychopharmacol.. 2005 Jul;19(4):414-21

Wheatley, D. “Kava and valerian in the treatment of stress-induced insomnia.” Phytoter Res. 2001 Sep;15(6):549-51

Hadley, S. et al. “Valerian.” Am Fam Physician. 2003 Apr;667(8):1755-8

Houghton, P.J. “The scientific basis for the reputed activity of valerian.” J Pharm Pharmacol. 1999 May;5195):515-12

Wheatley, D. “Stress-induced insomnia treated with kava and valerian: singly and in combination.” Hum Psychopharmacol. 2001 Jun;16(4):353-6

Pittler, M. H. et al. “Kava extract for treating anxiety.” Cochrane Database Syst Rev. 2003;(1):CD003383

Farag, N.H. et al. “A randomized-controlled trial of the effects of a traditional herbal supplement on sleep onset insomnia.” Complement Ther Med. 2003 Dec;11(4):223-5

Brown, R.P. et al. “Herbs and nutrients in the treatment of depression, anxiety, insomnia, migraine, and obesity.” J Psychiatr Pract. 2001 Mar;7(2):75-91

Shinomiya, K. et al. “Effects of kava-kava extract on the sleep-wake cycle in sleep-disturbed rats.” Psychopharmacology. 2005 Jul;180(3):564-9

Krenn, L. “[Passion flower (passiflora incarnata L.) – a reliable herbal sedative] [Article in German].” Wein Med Wochenschr. 2002;152(15-16):404-6

Schmitz, M. et al. “[Comparative study for assessing quality of life of patients with exogenous sleep disorders (temporary sleep onset and sleep interruption disorders) treated with a hops-valerian preparation and a benzodiazepine drug] [Article in German].” Wein Med Wochenschr. 1998;148(13):291-8

Cauffield, J. S. et al. “Dietary supplements used in the treatment of depression, anxiety, and sleep disorders.” Lippincotts Prim Care Pract. 1999 May-Jun;3(3):290-304

Lu, K. et al. “The acute effects of L-theanin in comparison with alprazolam on anticipatory anxiety in humans.” Hum Psychopharmacol. 2004 Oct;19(7):457-65

Awad, R. et al. “Phytochemical and biological analysis os skullcap (Scutellaria lateriflora L.): a medicinal plant with anxiolytic properties.” Phytomedicine. 2003 Nov;10(8):640-9

Shinomiya, K. et al. “Hypnotic activities of chamomile and passiflora extracts in sleep-disturbed rats.” Biol Pharm Bull. 2005 May;28(5):808-10

Lis, C. et al. “Why researchers at Cancer Treatment Centers of America are investigating melatonin as an anti-aging therapy in cancer treatment.” Life Extension. 2002 March:29-34

“Melatonin may lower blood pressure… Study: Sleep-aid hormone could treat hypertension.” Reuters. 2004 Jan 19.

Lissoni, P. “Is there a role for melatonin in supportive care?” Symposium: Supportive Care in Cancer, Denmark. 2001 Jun.

Karbownik, M. et al. “Renal toxicity of the carcinogen ALA: antioxidant effects of melatonin.” Cancer Letters. 2000;161:1-7

El-Sokkary, G. et al. “Melatonin reduces oxidative damage and increases survival of mice infected with schistosoma mansioni.” Free Radical Biology & Medicine. 2002;32(4):319-32

Gitto, E. et al. “Effects of melatonin treatment in septic newborns.” Pediatric Research. 2001;50(6):756-60

Reiter, R. J. et al. Melatonin: Your Body’s Natural Wonder Drug. Bantam, 1996.

Schmid, R.E. “Diabetes risk linked to sleep disruption.” Associated Press. 2007 Dec 31

L-Lysine and L-Proline

Albanese, A.A. et al. “Biochemical and nutritional effects of lysine-reinforced diets.” American Journal of Clinical Nutrition. 1995 Mar-Apr;3(2):121-8

Roomi, M.W. et al. “In vivo and in vitro antitumor effect of ascorbic acid, lysine, proline, and green tea extract on human melanoma cell line A2058.” in vivo. 2006;20:25-32

Albanese, A.A. et al. “Lysine and tryptophan content of proteins and their utilization for human growth.” American Journal of Clinical Nutrition. 1956 Mar-Apr;4(2):161-8

Smriga, M. et al. “Dietary L-Lysine deficiency increases stress-induced anxiety and fecal excretion in rats.” Journal of Nutrition. 2002;132:3744-6

Livalon

Ferenci, P. et al. “Randomized controlled trial or silymarin treatment in patients with cirrhosis of the liver.” Journal of Hepatology. 1989;9:105-113

Salmi, HA. et al. “Effect of silymarin on chemical, functional, and morphological alterations of the liver.” Scand J Gastroenterol. 1982;17:517-21

Chan, MK. et al. “Hepatitis B infection and renal transplantation: the absence of anti-delta antibodies and the possible beneficial effect of silymarin during acute episodes of hepatic dysfunction.” Nephrol Dial Transplant. 1989;4:297-301

Palasciano, G. et al. “The effect of silymarin on plasma levels of malon-dialdehyde in patients receiving long-term treatment with psychotropic drugs.” Current Therapeutic Research. 1994 May;55(5):537-45

Velussi, M. et al. “Silymarin reduces hyperinsulinemia, malondialdehyde levels, and daily insulin need in cirrhotic diabetic patients.” Current Therapeutic Research. 1993 May; 55(5):533-45

Nassuato, G. et al. “Effect of silibinin on biliary lipid composition: Experimental and clinical study.” Journal of Hepatology. 1991;12:290-5

Velussi, M. et al. “Long-term (12 months) treatment with an anti-oxidant drug (silymarin) is effective on hyperinsulinemia, exogenous insulin need and malondialdehyde levels in cirrhotic diabetic patients.” Journal of Hepatology. 1997;26:871-9

Agarwal, Z. “Tissue distribution of silibin, the major active constituent of silymarin, in mice and its association with enhancement of phase II enzymes: implications in cancer chemoprevention.” Carcinogenesis. 1999 Nov;20(11):2101-8

Agarwal, Z. “Modulation of mitogen-activated protein kinase activation and cell cycle regulators by the potent skin cancer preventive agent silymarin.” Biochem Biophys Res Commun. 1999 Sep 24;263(2):528-36

Boari, C. et al. “[Toxic occupational liver diseases. Therapeutic effects of silymarin] [Article in Italian].” Minerva Med. 1981 Oct 20;72(40):2679-88

Benda, L. et al. “[The influence of therapy with silymarin on the survival rate of patients with liver cirrhosis] [Article in German].” Wien Klin Wochenschr. 1980 Oct 10;92(19):678-83

Mingrino, F. et al. “[Clinical study of the herapeutic action of silymarin in acute infectious hepatitis in childhood] [Article in Italina].” Minera Pediatr. 1979 Mar 31;31(6):451-6

Kiesewetter, E. et al. “[Results of two double-blind studies on the ffect of silymarine in chronic hepatitis] [Article in German].” Leber Magen Darm. 1977 Oct;7(5):318-23

Muzes, G. et al. “[Effect of silimarin (Legalon) therapy on the antioxidant defense mechanism and lipid peroxidation in alcoholic liver disease.] [Article in Hungarian].” Orv Hetil. 1990 Apr 22;131(16):863-6

Feher, J. et al. “[Liver-protective action of silymarin therapy in chronic alcoholic liver disease] [Article in Hungarian].” Orv Hetil. 1989 Dec 17;130(51):2723-7

Szilard, S. et al. “Protective effect of Legalon in workers exposed to organic solvents.” Acta Med Hung. 1988;45(2):249-56

Feher, J. et al. “Oxidative stress in the liver and biliary tract diseases.” Scand J Gastroenterol Suppl. 1998;228:38-46

Lahiri-Chatterjee, M. et al. “A flavanoid antioxidant, silymarin, affords exceptionally high protection against tumor promotion in the SENCAR mouse skin tumorigenesis model.” Cancer Res. 1999 Feb 1;59(3):622-32

Skottova, N. et al. “Silymarin as a potential hypocholesterolaemic drug.” Physion Res. 1998;47(1):1-7

La Grange, L. “Protective effects of the flavonoid mixture, silymarin, on fetal rat brain and liver.” J Ethnopharmacol. 1999 Apr;65(1):53-61

Zi, X. et al. “Silibinin decreases prostate-specific antigen with cell growth inhibition via G1 arrest, leading to differentiation of prostate carcinoma cells: implications for prostate cancer intervention.” Proc Natl Acad Sci USA. 1999 Jun 22;96(13):7490-5

Sonnenbichler, J. “Stimulatory effects of silibinin and silicristin from the milk thistle Silybum marianum on kidney cells.” J Pharmacol Exp Ther. 1999 Sep;290(3):1375-83

“Can silibinin arrest cancer cell growth?” Life Extension. 2000 Jun:27-32

“Silymarin protects the pancreas.” Cellular and Molecular Life Sciences. 1997;53(11-12):917-20

Cowley, G. “Hepatitis: The insidious spread of a killer virus.” Newsweek. 2002 Apr 22:47-53

Magnesium & Potassium

Josephs, A. “Is a magnesium deficiency putting our children at risk?” Vitacost For Your Health Newsletter. 2005 May.

Wright, J. “Cures for everything from erectile dysfunction and ear infections, to kidney stones and cardiovascular disease.” Nutrition & Healing. 2007 Apr;14(2):1-8

Melatonin